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A close-up of a rustic pan filled with creamy chicken and Brussels sprout pasta, ready to be served.

Creamy Chicken Alfredo with Roasted Garlic Brussels Sprouts

Indulge in a rich and creamy chicken alfredo pasta perfectly complemented by tender, flavorful roasted garlic brussels sprouts. This dish is a hearty and satisfying meal that balances comfort with a touch of fresh greens.
Prep Time 20 minutes
Cook Time 30 minutes
Total Time 50 minutes
Servings: 4 servings
Course: Main Course
Cuisine: Italian-American
Calories: 850

Ingredients
  

For the Chicken
  • 1.5 lbs boneless, skinless chicken breasts cut into 1-inch cubes
  • 1 tbsp olive oil
  • 1/2 tsp salt
  • 1/4 tsp black pepper
  • 1/2 tsp garlic powder
  • 1/4 tsp dried Italian seasoning
For the Brussels Sprouts
  • 1 lb brussels sprouts trimmed and halved
  • 2 tbsp olive oil
  • 2 cloves garlic minced
  • 1/4 tsp salt
  • 1/8 tsp black pepper
  • 1 tbsp balsamic glaze optional, for drizzling
For the Pasta
  • 12 oz fettuccine or linguine pasta
  • 8 cups water for boiling
  • 1 tsp salt for pasta water
For the Alfredo Sauce
  • 4 tbsp unsalted butter
  • 2 cloves garlic minced
  • 1.5 cups heavy cream
  • 1 cup grated Parmesan cheese plus more for garnish
  • 1/4 tsp salt
  • 1/8 tsp black pepper
  • Pinch nutmeg optional
  • 1/4 cup reserved pasta water optional, for thinning

Equipment

  • Large Pot
  • Large Skillet or Dutch Oven
  • Baking Sheet or Air Fryer
  • Whisk
  • Tongs

Method
 

Prepare the Brussels Sprouts
  1. Preheat oven to 400°F (200°C) or air fryer to 375°F (190°C). In a bowl, toss halved brussels sprouts with 2 tbsp olive oil, minced garlic, 1/4 tsp salt, and 1/8 tsp black pepper.
  2. If baking: Spread brussels sprouts in a single layer on a baking sheet. Roast for 20-25 minutes, flipping halfway, until tender and lightly charred.
  3. If air frying: Place brussels sprouts in a single layer in the air fryer basket (cook in batches if necessary). Air fry for 12-15 minutes, shaking the basket halfway, until tender and crispy. Set aside.
Cook the Chicken
  1. While brussels sprouts cook, pat chicken cubes dry. In a medium bowl, toss chicken with 1 tbsp olive oil, 1/2 tsp salt, 1/4 tsp black pepper, 1/2 tsp garlic powder, and 1/4 tsp Italian seasoning.
  2. Heat a large skillet over medium-high heat. Add seasoned chicken and cook for 5-7 minutes, stirring occasionally, until browned and cooked through. Remove chicken from the skillet and set aside.
Cook the Pasta
  1. Bring a large pot of salted water (8 cups water, 1 tsp salt) to a rolling boil. Add fettuccine and cook according to package directions until al dente.
  2. Before draining, reserve 1/4 cup of pasta water. Drain the pasta and set aside.
Make the Alfredo Sauce
  1. In the same large skillet (no need to clean it after chicken), melt 4 tbsp unsalted butter over medium heat. Add 2 cloves minced garlic and sauté for 1 minute until fragrant.
  2. Slowly whisk in the heavy cream. Bring to a gentle simmer, then reduce heat to low.
  3. Gradually whisk in the grated Parmesan cheese until the sauce is smooth and thickened. Season with 1/4 tsp salt, 1/8 tsp black pepper, and a pinch of nutmeg if desired. If the sauce is too thick, add a tablespoon or two of reserved pasta water until desired consistency is reached.
Combine and Serve
  1. Add the cooked pasta and cooked chicken to the Alfredo sauce in the skillet. Toss gently to coat everything evenly.
  2. Divide the chicken alfredo among serving plates. Top each serving with the roasted garlic brussels sprouts. Drizzle with balsamic glaze if using, and garnish with extra Parmesan cheese and fresh parsley, if desired.

Notes

For a spicier kick, add a pinch of red pepper flakes to the Alfredo sauce. Leftovers can be stored in an airtight container in the refrigerator for up to 3 days. Reheat gently on the stovetop with a splash of milk or cream to loosen the sauce.